Thursday, February 27, 2020

Mapping Human Genetic Diversity on the Japanese Archipelago Assignment

Mapping Human Genetic Diversity on the Japanese Archipelago - Assignment Example Sara, and Li, Hu, which is titled â€Å"Mapping Human Genetic Diversity on the Japanese Archipelago† and published in Advances in anthropology 1.2 (2011): 19-25. The article explores the origin and diversification of East Asian populations, specifically the Japanese people. The origin of the current population on the island of Japan remains unclear to date (Ding et al. 1). According to archeological evidence, â€Å"there might have been two waves of migration to the Japanese archipelago in prehistory: the Paleolithic and Neolithic Jomonese and the Aeneolithic Yayoiese† (Ding et al. 1). However, Ding et al. affirm that the contributions of these two groups to the â€Å"contemporary Japanese population remain unclear† (1). Ding et al.’s work anticipates providing evidence from human genetics as a new approach to addressing this topic. Ding et al.’s research specifically examines the Japanese human population, a key contributor to East Asian population s. The migration of the Japanese population to their present island remains debatable, a feature that inspired Ding et al. to carry out this research. The investigation carried out by Ding et al. anticipates shading more light on the origin of the Japanese population. Japan forms a substantial proportion of the East Asian population. Controversy still rages as to how the Japan population arose. Two major waves of migration to the Japanese archipelago in prehistory have been proposed. Despite the fact that other theories exist, this research focused on the two major ones. â€Å"The first wave of migration began 50,000 years BP and reached a climax about 10,000 years BP, giving rise to the Jomonese culture† (qtd. in Hisao et al., 1998 ). Considered as the most recent, â€Å"a second wave of migration traveled to the Japanese archipelago at 23,000 years BP, giving rise to the Yayoi culture† (Ding et al. 1). According to fossil records and human remains, the Yayoiese appar ently dominated the Japanese archipelago finalizing their expansion at about 300AD (qtd. in Chard, 1974). However, â€Å"the evidence from cranial morphology does not support a complete replacement of the Jomonese by the Yayoiese† (qtd. in Hanihara, 1984). Several theories explaining the origin and diversification of the Japanese exist (qtd. in Mizoguchi, 1986). The research done by Ding et al. used DNA and Y chromosome analyses to conclude the origin of contemporary Japanese from both maternal and paternal lineages. Molecular anthropological evidence seems more reliable when compared to historical, archeological or osteological studies, since the genetic material used in molecular anthropology tends to be continuous and maintains its integrity as its passed on from generation to generation (Ding et al.1). Historical, archeological or osteological studies are unreliable. When compared to other materials used in molecular anthropology studies, â€Å"Y chromosome and mtDNA pro ve to be the most powerful because of their abundance and ease of extraction† (qtd. in Zhang et al., 2007). By combining Y chromosome single nucleotide polymorphisms (Y-SNPs) and Y-chromosome short tandem repeats (Y-STRs) information, none recombining region of Y chromosome (NRY) can be used to reveal the population migration and expansion history of modern human (Ding et al. 20). Studies have also shown that mtDNA has a maternal inheritance protocol and the population genetic characteristics of mtDNA resemble the NRY (Ding et al. 20). The investigation carried out by Ding et al. seems to present new data which support an existing theory. The research also re-analyzes existing data. The key objective aimed at illustrating the origin of the East Asian populations and specifically the Japanese people, using

Tuesday, February 11, 2020

Finance Case Study Example | Topics and Well Written Essays - 500 words

Finance - Case Study Example It should be noted that the selection of the family members for their respective positions are due to their being the relative of the founder and cannot be credited to their skills or experience in the industry. The current poor financial performance of G-III might be attributed to this set-up. Even though some of the important executives of G-III are not family members, the Goldfarbs are still in the highest ranks which place them in the position of making the final decisions even though some lower level executives disagree or might recommend otherwise. The efficiency of the management team is indicated by the financial position of G-III in comparison to other industry players. The case stated that in general, G-III has expanded market share from 2% to 10% with a compounded increase in revenue of 68% from 1986-1989. The market has grown faster at a rate of compounded 75% making G-III quite slow to respond to market expansion. Financially speaking, most of the company's resources are financed by riskier short term debt instead of long-term ones. As G-III is cash strapped, the company is illiquid and cannot pay its current obligations if they become due immediately. It also becomes apparent that the remedy for this will be from the capital which will be raised from the IPO.